Hi Andy. 1) Yes, this is possible, there is an up-fader mixing mode (I've put more detail regarding this in the e-mail that I sent you). 2) You don't have to disable the Serato Video plug-in (though, it may stop you accidentally launching it). It is recommended that you don't actually have Serato Video and MixEmergency running at the same time - as Serato Video will eat up a lot of the processing power of your computer. 3) It's not really possible to give a "best" place for these, as it depends what parts of MixEmergency you want to use, and they layout of Serato DJ that you're using. The main piece of advice that I can give on this though, is that you shouldn't place any windows of MixEmergency over parts of Serato DJ that get updated regularly (for example, the waveforms), as this can cause a slight degradation of performance.