@Nick I have a Rane 62 which is not mapped (to the ME) but lately i ve observed that when i start ME and Serato DJ, it triggers some FX presets/ Sequencer from launching ME. So i will go ahead and use my mouse to deactivate the FX Presets and also change the channel FX to none (for some strange reason its always the Kaleidoscope FX activated for both channels), then i start playing my set, further down the line this disabled Kaleidoscope FX gets reactivated. I have tried pushing all the buttons on my Mixer to see which one is sending the message but no joy. I have tried resetting midi in ME by going into the Midi set up but i'm still getting the FX triggered. Kindly advise Thanks